Suppressing aberrant phospholipase D1 signaling in 3xTg Alzheimer’s disease mouse model promotes synaptic resilience

Current approaches in treatment of Alzheimer’s disease (AD) is focused on early stages of cognitive decline. Identifying therapeutic targets that promote synaptic resilience during early stages may prevent progressive memory deficits by preserving memory mechanisms. We recently reported that the ind...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Bourne, Krystyn Z., Natarajan, Chandramouli, Perez, Carlos X. Medina, Tumurbaatar, Batbayar, Taglialatela, Giulio, Krishnan, Balaji
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6892889/
https://ncbi.nlm.nih.gov/pubmed/31797996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-54974-6
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