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Suppressing aberrant phospholipase D1 signaling in 3xTg Alzheimer’s disease mouse model promotes synaptic resilience

Current approaches in treatment of Alzheimer’s disease (AD) is focused on early stages of cognitive decline. Identifying therapeutic targets that promote synaptic resilience during early stages may prevent progressive memory deficits by preserving memory mechanisms. We recently reported that the ind...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Bourne, Krystyn Z., Natarajan, Chandramouli, Perez, Carlos X. Medina, Tumurbaatar, Batbayar, Taglialatela, Giulio, Krishnan, Balaji
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6892889/
https://ncbi.nlm.nih.gov/pubmed/31797996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-54974-6
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