Neutrophil extracellular traps drive inflammatory pathogenesis in malaria

Neutrophils are essential innate immune cells that extrude chromatin in the form of neutrophil extracellular traps (NETs). This form of cell death has potent immunostimulatory activity. We show that heme-induced NETs are essential for malaria pathogenesis. Using patient samples and a mouse model, we...

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Detaylı Bibliyografya
Yayımlandı:Sci Immunol
Asıl Yazarlar: Knackstedt, Sebastian Lorenz, Georgiadou, Athina, Apel, Falko, Abu-Abed, Ulrike, Moxon, Christopher A., Cunnington, Aubrey J., Raupach, Bärbel, Cunningham, Deirdre, Langhorne, Jean, Krüger, Renate, Barrera, Valentina, Harding, Simon P., Berg, Aase, Patel, Sam, Otterdal, Kari, Mordmüller, Benjamin, Schwarzer, Evelin, Brinkmann, Volker, Zychlinsky, Arturo, Amulic, Borko
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6892640/
https://ncbi.nlm.nih.gov/pubmed/31628160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.aaw0336
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