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Recruitment of the Ulp2 protease to the inner kinetochore prevents its hyper-sumoylation to ensure accurate chromosome segregation

The kinetochore is the central molecular machine that drives chromosome segregation in all eukaryotes. Genetic studies have suggested that protein sumoylation plays a role in regulating the inner kinetochore; however, the mechanism remains elusive. Here, we show that Saccharomyces cerevisiae Ulp2, a...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Suhandynata, Raymond T., Quan, Yun, Yang, Yusheng, Yuan, Wei-Tsung, Albuquerque, Claudio P., Zhou, Huilin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6892545/
https://ncbi.nlm.nih.gov/pubmed/31747400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008477
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