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GUCY2C-targeted cancer immunotherapy: past, present and future
For the last decade we have focused on guanylyl cyclase C (GUCY2C) as a potentially ideal target antigen for colorectal cancer immunotherapy. GUCY2C is expressed only in intestinal epithelial cells and by nearly 100% of colorectal cancers. We have developed and tested a recombinant adenoviral vector...
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| Veröffentlicht in: | Immunol Res |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6892460/ https://ncbi.nlm.nih.gov/pubmed/22038530 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12026-011-8253-7 |
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