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GUCY2C-targeted cancer immunotherapy: past, present and future

For the last decade we have focused on guanylyl cyclase C (GUCY2C) as a potentially ideal target antigen for colorectal cancer immunotherapy. GUCY2C is expressed only in intestinal epithelial cells and by nearly 100% of colorectal cancers. We have developed and tested a recombinant adenoviral vector...

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Detalhes bibliográficos
Publicado no:Immunol Res
Main Authors: Snook, Adam E., Magee, Michael S., Waldman, Scott A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6892460/
https://ncbi.nlm.nih.gov/pubmed/22038530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12026-011-8253-7
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