Lactoferrin CpG Island Hypermethylation and Decoupling of mRNA and Protein Expression in the Early Stages of Prostate Carcinogenesis

Lactoferrin (LTF) is an iron-binding protein canonically known for its innate and adaptive immune functions. LTF may also act as a tumor suppressor with antiproliferative action. LTF is inactivated genetically or epigenetically in various cancers, and a CpG island spanning the transcriptional start...

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Bibliografske podrobnosti
izdano v:Am J Pathol
Main Authors: Porter, Corey M., Haffner, Michael C., Kulac, Ibrahim, Maynard, Janielle P., Baena-Del Valle, Javier A., Isaacs, William B., Yegnasubramanian, Srinivasan, De Marzo, Angelo M., Sfanos, Karen S.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2019
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6892185/
https://ncbi.nlm.nih.gov/pubmed/31499027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2019.07.016
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