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Dialkylation of Indoles with Trichloroacetimidates to Access 3,3-Disubstituted Indolenines
2-Substituted indoles may be directly transformed to 3,3-dialkyl indolenines with trichloroacetimidate electrophiles and the Lewis acid TMSOTf. These reactions provide rapid access to complex indolenines which are present in a variety of complex natural products and medicinally relevant small molecu...
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| Udgivet i: | Molecules |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MDPI
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6891773/ https://ncbi.nlm.nih.gov/pubmed/31731742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24224143 |
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