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Synthesis of 3,3′-Disubstituted Indolenines Utilizing the Lewis Acid Catalyzed Alkylation of 2,3-Disubstituted Indoles with Trichloroacetimidates

Trichloroacetimidates function as effective electrophiles for the selective C3-alkylation of 2,3-disubstituted indoles to provide 3,3′-disubstituted indolenines. These indolenines are common synthetic intermediates that are often utilized in the synthesis of complex molecules. Effective reaction con...

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Publicat a:Synlett
Autors principals: Adhikari, Arijit A., Radal, Léa, Chisholm, John D.
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5636001/
https://ncbi.nlm.nih.gov/pubmed/29033500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0036-1588491
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