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Crystal structure of the Wheat dwarf virus Rep domain

The Rep domain of Wheat dwarf virus (WDV Rep) is an HUH endonuclease involved in rolling-circle replication. HUH endonucleases coordinate a metal ion to enable the nicking of a specific ssDNA sequence and the subsequent formation of an intermediate phosphotyrosine bond. This covalent protein–ssDNA a...

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Detalhes bibliográficos
Publicado no:Acta Crystallogr F Struct Biol Commun
Main Authors: Everett, Blake A., Litzau, Lauren A., Tompkins, Kassidy, Shi, Ke, Nelson, Andrew, Aihara, Hideki, Evans III, Robert L., Gordon, Wendy R.
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6891580/
https://ncbi.nlm.nih.gov/pubmed/31797816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X19015796
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