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Crystal structure of lipid A disaccharide synthase LpxB from Escherichia coli

Most Gram-negative bacteria are surrounded by a glycolipid called lipopolysaccharide (LPS), which forms a barrier to hydrophobic toxins and, in pathogenic bacteria, is a virulence factor. During LPS biosynthesis, a membrane-associated glycosyltransferase (LpxB) forms a tetra-acylated disaccharide th...

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Detalles Bibliográficos
Publicado en:Nat Commun
Main Authors: Bohl, Heather O., Shi, Ke, Lee, John K., Aihara, Hideki
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5785501/
https://ncbi.nlm.nih.gov/pubmed/29371662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02712-9
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