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ENPP1, an Old Enzyme with New Functions, and Small Molecule Inhibitors—A STING in the Tale of ENPP1

Ectonucleotide pyrophosphatase/phosphodiesterase I (ENPP1) was identified several decades ago as a type II transmembrane glycoprotein with nucleotide pyrophosphatase and phosphodiesterase enzymatic activities, critical for purinergic signaling. Recently, ENPP1 has emerged as a critical phosphodieste...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Onyedibe, Kenneth I., Wang, Modi, Sintim, Herman O.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6891441/
https://ncbi.nlm.nih.gov/pubmed/31752288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24224192
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