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Iminosugars counteract the downregulation of the interferon γ receptor by dengue virus
The antiviral mechanism of action of iminosugars against many enveloped viruses is hypothesized to be a consequence of misfolding of viral N-linked glycoproteins through inhibition of host endoplasmic reticulum α-glucosidase enzymes. Iminosugar treatment of dengue virus (DENV) infection results in r...
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| Pubblicato in: | Antiviral Res |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Elsevier
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6891261/ https://ncbi.nlm.nih.gov/pubmed/31306674 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2019.104551 |
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