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Liposome-Mediated Delivery of Iminosugars Enhances Efficacy against Dengue Virus In Vivo
A key challenge faced by promising antiviral drugs, such as iminosugars, is in vivo delivery to achieve effective levels of drug without toxicity. Four iminosugars, all deoxynojirimycin (DNJ) derivatives—N-butyl DNJ (NB-DNJ), N-nonyl DNJ, N-(9-methoxynonyl) DNJ, and N-(6′-[4″-azido-2″-nitrophenylami...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Microbiology
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3497178/ https://ncbi.nlm.nih.gov/pubmed/23070155 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01554-12 |
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