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Hyaluronic acid binding to TLR4 promotes proliferation and blocks apoptosis in colon cancer
Hyaluronic acid (HA), a constituent of the extracellular matrix, promotes colorectal cancer (CRC) growth. CD44 is a relevant HA receptor in this context. However, HA is also a ligand for TLR4, a receptor of significance in CRC. In this study we examine the relative contribution of HA interactions wi...
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| Publié dans: | Mol Cancer Ther |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6891171/ https://ncbi.nlm.nih.gov/pubmed/31484704 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-18-1225 |
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