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CD44 and TLR4 mediate hyaluronic acid regulation of Lgr5(+) stem cell proliferation, crypt fission, and intestinal growth in postnatal and adult mice
Hyaluronic acid, a glycosaminoglycan in the extracellular matrix, binds to CD44 and Toll-like receptor 4 (TLR4). We previously addressed the role of hyaluronic acid in small intestinal and colonic growth in mice. We addressed the role of exogenous hyaluronic acid by giving hyaluronic acid intraperit...
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| Publicado no: | Am J Physiol Gastrointest Liver Physiol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4669354/ https://ncbi.nlm.nih.gov/pubmed/26505972 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00123.2015 |
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