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Rekindling RNAi Therapy: Materials Design Requirements for In Vivo siRNA Delivery
With the recent FDA approval of the first siRNA-derived therapeutic, RNA interference (RNAi)-mediated gene therapy is undergoing a transition from research to the clinical space. The primary obstacle to realization of RNAi therapy has been the delivery of oligonucleotide payloads. This review aims t...
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| Vydáno v: | Adv Mater |
|---|---|
| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6891135/ https://ncbi.nlm.nih.gov/pubmed/31566258 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adma.201903637 |
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