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Rekindling RNAi Therapy: Materials Design Requirements for In Vivo siRNA Delivery

With the recent FDA approval of the first siRNA-derived therapeutic, RNA interference (RNAi)-mediated gene therapy is undergoing a transition from research to the clinical space. The primary obstacle to realization of RNAi therapy has been the delivery of oligonucleotide payloads. This review aims t...

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Bibliografische gegevens
Gepubliceerd in:Adv Mater
Hoofdauteurs: Kim, Byungji, Park, Ji-Ho, Sailor, Michael J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6891135/
https://ncbi.nlm.nih.gov/pubmed/31566258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adma.201903637
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