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Delineating the contribution of Spc105-bound PP1 to spindle checkpoint silencing and kinetochore microtubule attachment regulation

Accurate chromosome segregation during cell division requires the spindle assembly checkpoint (SAC), which detects unattached kinetochores, and an error correction mechanism that destabilizes incorrect kinetochore–microtubule attachments. While the SAC and error correction are both regulated by prot...

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Опубликовано в: :J Cell Biol
Главные авторы: Roy, Babhrubahan, Verma, Vikash, Sim, Janice, Fontan, Adrienne, Joglekar, Ajit P.
Формат: Artigo
Язык:Inglês
Опубликовано: Rockefeller University Press 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6891095/
https://ncbi.nlm.nih.gov/pubmed/31649151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201810172
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