CDK1-mediated CENP-C phosphorylation modulates CENP-A binding and mitotic kinetochore localization

The kinetochore is essential for faithful chromosome segregation during mitosis. To form a functional kinetochore, constitutive centromere-associated network (CCAN) proteins are assembled on the centromere chromatin that contains the centromere-specific histone CENP-A. CENP-C, a CCAN protein, direct...

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Udgivet i:J Cell Biol
Main Authors: Watanabe, Reito, Hara, Masatoshi, Okumura, Ei-ichi, Hervé, Solène, Fachinetti, Daniele, Ariyoshi, Mariko, Fukagawa, Tatsuo
Format: Artigo
Sprog:Inglês
Udgivet: Rockefeller University Press 2019
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6891089/
https://ncbi.nlm.nih.gov/pubmed/31676716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201907006
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