Drug Repurposing of Bromodomain Inhibitors as Potential Novel Therapeutic Leads for Lymphatic Filariasis Guided by Multispecies Transcriptomics

To better understand the transcriptomic interplay of organisms associated with lymphatic filariasis, we conducted multispecies transcriptome sequencing (RNA-Seq) on the filarial nematode Brugia malayi, its Wolbachia endosymbiont wBm, and its laboratory vector Aedes aegypti across the entire B. malay...

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Detalhes bibliográficos
Publicado no:mSystems
Main Authors: Chung, Matthew, Teigen, Laura E., Libro, Silvia, Bromley, Robin E., Olley, Dustin, Kumar, Nikhil, Sadzewicz, Lisa, Tallon, Luke J., Mahurkar, Anup, Foster, Jeremy M., Michalski, Michelle L., Dunning Hotopp, Julie C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6890932/
https://ncbi.nlm.nih.gov/pubmed/31796568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSystems.00596-19
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