Repurposing Auranofin as a Lead Candidate for Treatment of Lymphatic Filariasis and Onchocerciasis

Two major human diseases caused by filariid nematodes are onchocerciasis, or river blindness, and lymphatic filariasis, which can lead to elephantiasis. The drugs ivermectin, diethylcarbamazine (DEC), and albendazole are used in control programs for these diseases, but are mainly effective against t...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Bulman, Christina A., Bidlow, Chelsea M., Lustigman, Sara, Cho-Ngwa, Fidelis, Williams, David, Rascón, Jr, Alberto A., Tricoche, Nancy, Samje, Moses, Bell, Aaron, Suzuki, Brian, Lim, K. C., Supakorndej, Nonglak, Supakorndej, Prasit, Wolfe, Alan R., Knudsen, Giselle M., Chen, Steven, Wilson, Chris, Ang, Kean-Hooi, Arkin, Michelle, Gut, Jiri, Franklin, Chris, Marcellino, Chris, McKerrow, James H., Debnath, Anjan, Sakanari, Judy A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4336141/
https://ncbi.nlm.nih.gov/pubmed/25700363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003534
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