Barrier-to-autointegration factor 1 (Banf1) regulates poly [ADP-ribose] polymerase 1 (PARP1) activity following oxidative DNA damage

The DNA repair capacity of human cells declines with age, in a process that is not clearly understood. Mutation of the nuclear envelope protein barrier-to-autointegration factor 1 (Banf1) has previously been shown to cause a human progeroid disorder, Néstor–Guillermo progeria syndrome (NGPS). The un...

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Publicado no:Nat Commun
Main Authors: Bolderson, Emma, Burgess, Joshua T., Li, Jun, Gandhi, Neha S., Boucher, Didier, Croft, Laura V., Beard, Samuel, Plowman, Jennifer J., Suraweera, Amila, Adams, Mark N., Naqi, Ali, Zhang, Shu-Dong, Sinclair, David A., O’Byrne, Kenneth J., Richard, Derek J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6890647/
https://ncbi.nlm.nih.gov/pubmed/31796734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13167-5
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