Repression of phagocytosis by human CD33 is not conserved with mouse CD33

CD33 is an immunomodulatory receptor linked to Alzheimer’s disease (AD) susceptibility via regulation of phagocytosis in microglia. Divergent features between human CD33 (hCD33) and murine CD33 (mCD33) include a unique transmembrane lysine in mCD33 and cytoplasmic tyrosine in hCD33. The functional c...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Commun Biol
Main Authors: Bhattacherjee, Abhishek, Rodrigues, Emily, Jung, Jaesoo, Luzentales-Simpson, Matthew, Enterina, Jhon R., Galleguillos, Danny, St. Laurent, Chris D., Nakhaei-Nejad, Maryam, Fuchsberger, Felix F., Streith, Laura, Wang, Qian, Kawasaki, Norihito, Duan, Shiteng, Bains, Arjun, Paulson, James C., Rademacher, Christoph, Giuliani, Fabrizio, Sipione, Simonetta, Macauley, Matthew S.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6890642/
https://ncbi.nlm.nih.gov/pubmed/31815204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0698-6
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