Combination Therapy Targeting Platelet Activation and Virus Replication Protects Mice against Lethal Influenza Pneumonia

Excessive neutrophils recruited during influenza pneumonia contribute to severe lung pathology through induction of neutrophil extracellular traps (NETs) and release of extracellular histones. We have recently shown that activation of platelets during influenza enhances pulmonary microvascular throm...

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Dettagli Bibliografici
Pubblicato in:Am J Respir Cell Mol Biol
Autori principali: Pulavendran, Sivasami, Rudd, Jennifer M., Maram, Prasanthi, Thomas, Paul G., Akhilesh, Ramachandran, Malayer, Jerry R., Chow, Vincent T. K., Teluguakula, Narasaraju
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Thoracic Society 2019
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6890408/
https://ncbi.nlm.nih.gov/pubmed/31070937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2018-0196OC
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