Combination Therapy Targeting Platelet Activation and Virus Replication Protects Mice against Lethal Influenza Pneumonia

Excessive neutrophils recruited during influenza pneumonia contribute to severe lung pathology through induction of neutrophil extracellular traps (NETs) and release of extracellular histones. We have recently shown that activation of platelets during influenza enhances pulmonary microvascular throm...

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Dades bibliogràfiques
Publicat a:Am J Respir Cell Mol Biol
Autors principals: Pulavendran, Sivasami, Rudd, Jennifer M., Maram, Prasanthi, Thomas, Paul G., Akhilesh, Ramachandran, Malayer, Jerry R., Chow, Vincent T. K., Teluguakula, Narasaraju
Format: Artigo
Idioma:Inglês
Publicat: American Thoracic Society 2019
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6890408/
https://ncbi.nlm.nih.gov/pubmed/31070937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2018-0196OC
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