Combination Therapy Targeting Platelet Activation and Virus Replication Protects Mice against Lethal Influenza Pneumonia

Excessive neutrophils recruited during influenza pneumonia contribute to severe lung pathology through induction of neutrophil extracellular traps (NETs) and release of extracellular histones. We have recently shown that activation of platelets during influenza enhances pulmonary microvascular throm...

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發表在:Am J Respir Cell Mol Biol
Main Authors: Pulavendran, Sivasami, Rudd, Jennifer M., Maram, Prasanthi, Thomas, Paul G., Akhilesh, Ramachandran, Malayer, Jerry R., Chow, Vincent T. K., Teluguakula, Narasaraju
格式: Artigo
語言:Inglês
出版: American Thoracic Society 2019
主題:
Original Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6890408/
https://ncbi.nlm.nih.gov/pubmed/31070937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2018-0196OC
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