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A screening-based approach identifies cell cycle regulators AURKA, CHK1 and PLK1 as targetable regulators of chondrosarcoma cell survival

Chondrosarcomas are malignant cartilage tumors that are relatively resistant towards conventional therapeutic approaches. Kinase inhibitors have been investigated and shown successful for several different cancer types. In this study we aimed at identifying kinase inhibitors that inhibit the surviva...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Bone Oncol
Main Authors: de Jong, Yvonne, Bennani, Fairuz, van Oosterwijk, Jolieke G., Alberti, Gaia, Baranski, Zuzanna, Wijers-Koster, Pauline, Venneker, Sanne, Briaire-de Bruijn, Inge H., van de Akker, Brendy E., Baelde, Hans, Cleton-Jansen, Anne-Marie, van de Water, Bob, Danen, Erik H.J., Bovée, Judith V.M.G.
פורמט: Artigo
שפה:Inglês
יצא לאור: Elsevier 2019
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6889735/
https://ncbi.nlm.nih.gov/pubmed/31832331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbo.2019.100268
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