A screening-based approach identifies cell cycle regulators AURKA, CHK1 and PLK1 as targetable regulators of chondrosarcoma cell survival

Chondrosarcomas are malignant cartilage tumors that are relatively resistant towards conventional therapeutic approaches. Kinase inhibitors have been investigated and shown successful for several different cancer types. In this study we aimed at identifying kinase inhibitors that inhibit the surviva...

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Detaylı Bibliyografya
Yayımlandı:J Bone Oncol
Asıl Yazarlar: de Jong, Yvonne, Bennani, Fairuz, van Oosterwijk, Jolieke G., Alberti, Gaia, Baranski, Zuzanna, Wijers-Koster, Pauline, Venneker, Sanne, Briaire-de Bruijn, Inge H., van de Akker, Brendy E., Baelde, Hans, Cleton-Jansen, Anne-Marie, van de Water, Bob, Danen, Erik H.J., Bovée, Judith V.M.G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2019
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6889735/
https://ncbi.nlm.nih.gov/pubmed/31832331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbo.2019.100268
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