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Senescent cell turnover slows with age providing an explanation for the Gompertz law
A causal factor in mammalian aging is the accumulation of senescent cells (SnCs). SnCs cause chronic inflammation, and removing SnCs decelerates aging in mice. Despite their importance, turnover rates of SnCs are unknown, and their connection to aging dynamics is unclear. Here we use longitudinal Sn...
Enregistré dans:
| Publié dans: | Nat Commun |
|---|---|
| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6889273/ https://ncbi.nlm.nih.gov/pubmed/31792199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13192-4 |
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