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Senescent cell turnover slows with age providing an explanation for the Gompertz law
A causal factor in mammalian aging is the accumulation of senescent cells (SnCs). SnCs cause chronic inflammation, and removing SnCs decelerates aging in mice. Despite their importance, turnover rates of SnCs are unknown, and their connection to aging dynamics is unclear. Here we use longitudinal Sn...
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| 出版年: | Nat Commun |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6889273/ https://ncbi.nlm.nih.gov/pubmed/31792199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13192-4 |
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