Systemic MEK inhibition enhances the efficacy of 5-aminolevulinic acid-photodynamic therapy

BACKGROUND: Protoporphyrin IX (PpIX) gets accumulated preferentially in 5-aminolevulinic acid (5-ALA)-treated cancer cells. Photodynamic therapy (PDT) utilises the accumulated PpIX to trigger cell death by light-induced generation of reactive oxygen species (ROS). We previously demonstrated that onc...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Br J Cancer
Huvudupphovsmän: Chelakkot, Vipin Shankar, Som, Jayoti, Yoshioka, Ema, Rice, Chantel P., Rutihinda, Suzette G., Hirasawa, Kensuke
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2019
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6889170/
https://ncbi.nlm.nih.gov/pubmed/31551581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-019-0586-3
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk