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An integrated screening system for the selection of exemplary substrates for natural and engineered cytochrome P450s

Information about substrate and product selectivity is critical for understanding the function of cytochrome P450 monooxygenases. In addition, comprehensive understanding of changes in substrate selectivity of P450 upon amino acid mutation would enable the design and creation of engineered P450s wit...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Kanoh, Naoki, Kawamata-Asano, Ayano, Suzuki, Kana, Takahashi, Yusuke, Miyazawa, Takeshi, Nakamura, Takemichi, Moriya, Takashi, Hirano, Hiroyuki, Osada, Hiroyuki, Iwabuchi, Yoshiharu, Takahashi, Shunji
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6888865/
https://ncbi.nlm.nih.gov/pubmed/31792277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-54473-8
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