Up‐regulation of miR‐let7a‐5p Leads to Decreased Expression of ABCC2 in Obstructive Cholestasis

Adenosine triphosphate–binding cassette subfamily C member 2 (ABCC2/Abcc2) is critically important to biliary excretion of many endobiotic and xenobiotic compounds, and is a major driving force for bile acid–independent bile flow. Abcc2 expression is reduced at the messenger RNA (mRNA) and protein l...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Hepatol Commun
Hauptverfasser: Balasubramaniyan, Natarajan, Devereaux, Michael W., Orlicky, David J., Sokol, Ronald J., Suchy, Frederick J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
Schlagworte:
Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6887930/
https://ncbi.nlm.nih.gov/pubmed/31832574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1433
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