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Nuclear factor-κB regulates the expression of multiple genes encoding liver transport proteins

In this study we identified the mechanisms underlying the inhibitory effects of NF-κB on the expression of genes encoding multiple liver transport proteins. Well-conserved NF-κB binding sites were found in the promoters of farnesoid X receptor (FXR)-target genes. An electromobility shift assay (EMSA...

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Pubblicato in:Am J Physiol Gastrointest Liver Physiol
Autori principali: Balasubramaniyan, Natarajan, Ananthanarayanan, Meenakshisundaram, Suchy, Frederick J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836129/
https://ncbi.nlm.nih.gov/pubmed/26867564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00363.2015
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