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The Dichotomous Nature of AZ5104 (an EGFR Inhibitor) Towards RORγ and RORγT
The RORC (RAR related orphan receptor C) gene produces two isoforms by alternative promoter usage: RORγ (nuclear receptor ROR-gamma isoform 1) and RORγT (nuclear receptor ROR-gamma isoform 1). Both proteins have distinct tissue distributions and are involved in several physiological processes, inclu...
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| Gepubliceerd in: | Int J Mol Sci |
|---|---|
| Hoofdauteurs: | , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
MDPI
2019
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6887705/ https://ncbi.nlm.nih.gov/pubmed/31744223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20225780 |
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