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An mRNA-binding channel in the ES6S region of the translation 48S-PIC promotes RNA unwinding and scanning

Loading of mRNA onto the ribosomal 43S pre-initiation complex (PIC) and its subsequent scanning require the removal of the secondary structure of the by RNA helicases such as eIF4A. However, the topology and mechanics of the scanning complex bound to mRNA (48S-PIC) and the influence of its solvent-s...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:eLife
Asıl Yazarlar: Díaz-López, Irene, Toribio, René, Berlanga, Juan José, Ventoso, Iván
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: eLife Sciences Publications, Ltd 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6887119/
https://ncbi.nlm.nih.gov/pubmed/31789591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.48246
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