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An mRNA-binding channel in the ES6S region of the translation 48S-PIC promotes RNA unwinding and scanning

Loading of mRNA onto the ribosomal 43S pre-initiation complex (PIC) and its subsequent scanning require the removal of the secondary structure of the by RNA helicases such as eIF4A. However, the topology and mechanics of the scanning complex bound to mRNA (48S-PIC) and the influence of its solvent-s...

詳細記述

保存先:
書誌詳細
出版年:eLife
主要な著者: Díaz-López, Irene, Toribio, René, Berlanga, Juan José, Ventoso, Iván
フォーマット: Artigo
言語:Inglês
出版事項: eLife Sciences Publications, Ltd 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6887119/
https://ncbi.nlm.nih.gov/pubmed/31789591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.48246
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