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Targeting CpG Adjuvant to Lymph Node via Dextran Conjugate Enhances Antitumor Immunotherapy

Nucleic acid based adjuvants recognized by Toll-like receptors (TLR) are potent immune system stimulants that can augment the antitumor immune responses in an antigen-specific manner. However, their clinical uses as vaccine adjuvants are limited primarily due to lack of accumulation in the lymph nod...

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Bibliografske podrobnosti
izdano v:Bioconjug Chem
Main Authors: Zhang, Weidong, An, Myunggi, Xi, Jingchao, Liu, Haipeng
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6886672/
https://ncbi.nlm.nih.gov/pubmed/28644608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.7b00313
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