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Glycoengineering of chimeric antigen receptor (CAR) T-cells to enforce E-selectin binding

Tissue colonization (homing) by blood-borne cells critically hinges on the ability of the cells to adhere to vascular endothelium with sufficient strength to overcome prevailing hemodynamic shear stress. These adhesive interactions are most effectively engendered via binding of the endothelial lecti...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Mondal, Nandini, Silva, Mariana, Castano, Ana P., Maus, Marcela V., Sackstein, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6885642/
https://ncbi.nlm.nih.gov/pubmed/31628196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011134
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