Silencing α1,3-Fucosyltransferases in Human Leukocytes Reveals a Role for FUT9 Enzyme during E-selectin-mediated Cell Adhesion

Leukocyte adhesion during inflammation is initiated by the binding of sialofucosylated carbohydrates expressed on leukocytes to endothelial E/P-selectin. Although the glycosyltransferases (glycoTs) constructing selectin-ligands have largely been identified using knock-out mice, important differences...

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Detalhes bibliográficos
Main Authors: Buffone, Alexander, Mondal, Nandini, Gupta, Rohitesh, McHugh, Kyle P., Lau, Joseph T. Y., Neelamegham, Sriram
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Glycobiology and Extracellular Matrices
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548472/
https://ncbi.nlm.nih.gov/pubmed/23192350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.400929
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