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Gα-13 induces CXC motif chemokine ligand 5 expression in prostate cancer cells by transactivating NF-κB
GNA13, the α subunit of a heterotrimeric G protein, mediates signaling through G-protein–coupled receptors (GPCRs). GNA13 is up-regulated in many solid tumors, including prostate cancer, where it contributes to tumor initiation, drug resistance, and metastasis. To better understand how GNA13 contrib...
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| Publicado no: | J Biol Chem |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6885619/ https://ncbi.nlm.nih.gov/pubmed/31636124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.010018 |
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