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CD137 ligand feedback upregulates PD‐L1 expression on lung cancer via T cell production of IFN‐γ

BACKGROUND: The expression of PD‐L1 and its regulation in tumors remains unclear. The importance of IFN‐γ in upregulating the PD‐L1 expression in various tumors, and the effects of other essential cytokines in the tumor microenvironment (TME), need to be further elucidated. METHODS: Constitutive exp...

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Bibliografski detalji
Izdano u:Thorac Cancer
Glavni autori: Wang, Helin, Yan, Zhuohong, Hao, Jianqing, Yang, Bin, Wang, Jinghui, Yi, Ling, Wang, Xiaojue, Li, Shuping, Zhang, Hongtao, Zhang, Shucai
Format: Artigo
Jezik:Inglês
Izdano: John Wiley & Sons Australia, Ltd 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6885434/
https://ncbi.nlm.nih.gov/pubmed/31625289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1759-7714.13207
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