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All-trans-retinoic acid generation is an antidotal clearance pathway for all-trans-retinal in the retina
The present study was designed to analyze the metabolites of all-trans-retinal (atRal) and compare the cytotoxicity of atRal versus its derivative all-trans-retinoic acid (atRA) in human retinal pigment epithelial (RPE) cells. We confirmed that atRA was produced in normal pig neural retina and RPE....
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| Publicado en: | J Zhejiang Univ Sci B |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Zhejiang University Press
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6885407/ https://ncbi.nlm.nih.gov/pubmed/31749343 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1631/jzus.B1900271 |
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