All-trans-retinoic acid antagonizes the hedgehog pathway by inducing patched

Male germ cell tumors (GCTs) are a model for a curable solid tumor. GCTs can differentiate into mature teratomas. Embryonal carcinomas (ECs) represent the stem cell compartment of GCTs and are the malignant counterpart to embryonic stem (ES) cells. GCTs and EC cells are useful to investigate differe...

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Bibliografiske detaljer
Main Authors: Busch, Alexander M, Galimberti, Fabrizio, Nehls, Kristen E, Roengvoraphoj, Monic, Sekula, David, Li, Bin, Guo, Yongli, DiRenzo, James, Fiering, Steven N, Spinella, Michael J, Robbins, David J, Memoli, Vincent A, Freemantle, Sarah J, Dmitrovsky, Ethan
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2014
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979824/
https://ncbi.nlm.nih.gov/pubmed/24496080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.27821
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