All-trans-retinoic acid antagonizes the hedgehog pathway by inducing patched

Male germ cell tumors (GCTs) are a model for a curable solid tumor. GCTs can differentiate into mature teratomas. Embryonal carcinomas (ECs) represent the stem cell compartment of GCTs and are the malignant counterpart to embryonic stem (ES) cells. GCTs and EC cells are useful to investigate differe...

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Hlavní autoři: Busch, Alexander M, Galimberti, Fabrizio, Nehls, Kristen E, Roengvoraphoj, Monic, Sekula, David, Li, Bin, Guo, Yongli, DiRenzo, James, Fiering, Steven N, Spinella, Michael J, Robbins, David J, Memoli, Vincent A, Freemantle, Sarah J, Dmitrovsky, Ethan
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2014
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979824/
https://ncbi.nlm.nih.gov/pubmed/24496080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.27821
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