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Dexmedetomidine Attenuates Orthotopic Liver Transplantation-Induced Acute Gut Injury via α(2)-Adrenergic Receptor-Dependent Suppression of Oxidative Stress

Patients with orthotopic liver transplantation (OLT) frequently develop acute gut injury (AGI), and dexmedetomidine (Dex) has been reported to exert a protective effect against AGI. We investigated whether Dex protects against AGI through antioxidative stress effects by the Nrf2/HO-1 antioxidative s...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Lv, Peibiao, Chen, Tufeng, Liu, Peibin, Zheng, Lei, Tian, Jingling, Tan, Fan, Chen, Jiaxin, Deng, Yingqing, Li, Jun, Cai, Jun, Chi, Xinjin
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6885230/
https://ncbi.nlm.nih.gov/pubmed/31827710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/9426368
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