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Accelerated decline in cognition in a mouse model of increased oxidative stress

Mice deficient in the antioxidant enzyme Cu/Zn-superoxide dismutase (Sod1KO mice) have a significant reduction in lifespan, exhibit many phenotypes of accelerated aging, and have high levels of oxidative stress in various tissues. Age-associated cognitive decline is a hallmark of aging and the incre...

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Bibliografiske detaljer
Udgivet i:GeroScience
Main Authors: Logan, Sreemathi, Royce, Gordon H., Owen, Daniel, Farley, Julie, Ranjo-Bishop, Michelle, Sonntag, William E., Deepa, Sathyaseelan S.
Format: Artigo
Sprog:Inglês
Udgivet: Springer International Publishing 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6885085/
https://ncbi.nlm.nih.gov/pubmed/31641924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-019-00105-y
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