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Development of an ex vivo preclinical respiratory model of idiopathic pulmonary fibrosis for aerosol regional studies

Idiopathic pulmonary fibrosis is a progressive disease with unsatisfactory systemic treatments. Aerosol drug delivery to the lungs is expected to be an interesting route of administration. However, due to the alterations of lung compliance caused by fibrosis, local delivery remains challenging. This...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Montigaud, Yoann, Périnel-Ragey, Sophie, Plantier, Laurent, Leclerc, Lara, Goy, Clémence, Clotagatide, Anthony, Prévôt, Nathalie, Pourchez, Jérémie
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6884587/
https://ncbi.nlm.nih.gov/pubmed/31784683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-54479-2
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