Development of an ex vivo human-porcine respiratory model for preclinical studies

Anatomical models to study aerosol delivery impose huge limitations and extrapolation to humans remains controversial. This study aimed to develop and validate an ex vivo human-like respiratory tract model easy to use and relevant to compare to in vivo human data. A human plastinated head is connect...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Perinel, Sophie, Pourchez, Jérémie, Leclerc, Lara, Avet, John, Durand, Marc, Prévôt, Nathalie, Cottier, Michèle, Vergnon, Jean M.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5324051/
https://ncbi.nlm.nih.gov/pubmed/28233793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43121
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