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Development of an ex vivo human-porcine respiratory model for preclinical studies

Anatomical models to study aerosol delivery impose huge limitations and extrapolation to humans remains controversial. This study aimed to develop and validate an ex vivo human-like respiratory tract model easy to use and relevant to compare to in vivo human data. A human plastinated head is connect...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Perinel, Sophie, Pourchez, Jérémie, Leclerc, Lara, Avet, John, Durand, Marc, Prévôt, Nathalie, Cottier, Michèle, Vergnon, Jean M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5324051/
https://ncbi.nlm.nih.gov/pubmed/28233793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43121
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