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Development of an ex vivo preclinical respiratory model of idiopathic pulmonary fibrosis for aerosol regional studies

Idiopathic pulmonary fibrosis is a progressive disease with unsatisfactory systemic treatments. Aerosol drug delivery to the lungs is expected to be an interesting route of administration. However, due to the alterations of lung compliance caused by fibrosis, local delivery remains challenging. This...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Montigaud, Yoann, Périnel-Ragey, Sophie, Plantier, Laurent, Leclerc, Lara, Goy, Clémence, Clotagatide, Anthony, Prévôt, Nathalie, Pourchez, Jérémie
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6884587/
https://ncbi.nlm.nih.gov/pubmed/31784683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-54479-2
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